TY - GEN AU - Sharlow,Elizabeth R AU - Leimgruber,Stephanie AU - Shun,Tong Ying AU - Lazo,John S TI - Development and implementation of a miniaturized high-throughput time-resolved fluorescence energy transfer assay to identify small molecule inhibitors of polo-like kinase 1 SN - 1540-658X PY - 2008///0225 KW - Blotting, Western KW - Cell Cycle Proteins KW - antagonists & inhibitors KW - Data Interpretation, Statistical KW - Drug Design KW - Drug Evaluation, Preclinical KW - Enzyme Inhibitors KW - chemical synthesis KW - Fluorescence Resonance Energy Transfer KW - Fluorometry KW - Freezing KW - Hydrogen-Ion Concentration KW - Indicators and Reagents KW - Kinetics KW - Miniaturization KW - Protein Kinase C KW - Protein Serine-Threonine Kinases KW - Proto-Oncogene Proteins KW - Reproducibility of Results KW - Silver Staining KW - Substrate Specificity KW - Temperature KW - Polo-Like Kinase 1 N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural UR - https://doi.org/10.1089/adt.2007.102 ER -