Shen, Yuh-Chiang <br/><br/>
Dimemorfan protects rats against ischemic stroke through activation of sigma-1 receptor-mediated mechanisms by decreasing glutamate accumulation.  [electronic resource] 

 -  Journal of neurochemistry  Jan 2008 
 - 558-72 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1471-4159 
<br/><br/><label>Standard No.: </label>10.1111/j.1471-4159.2007.05058.x  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Analysis of Variance<br/>Animals<br/>Brain Infarction--etiology<br/>Brain Ischemia--drug therapy<br/>Chemokine CCL2--metabolism<br/>Disease Models, Animal<br/>Dose-Response Relationship, Drug<br/>Gene Expression Regulation--drug effects<br/>Glutamic Acid--metabolism<br/>Lipid Peroxidation--drug effects<br/>Male<br/>Morphinans--therapeutic use<br/>Morpholines--pharmacology<br/>Nitric Oxide Synthase--metabolism<br/>Peroxidase--metabolism<br/>Protein Serine-Threonine Kinases--metabolism<br/>Rats<br/>Rats, Long-Evans<br/>Receptors, sigma--agonists<br/>Reperfusion Injury--prevention & control<br/>STAT1 Transcription Factor--metabolism<br/>Signal Transduction--drug effects<br/>Sigma-1 Receptor<br/>NF-kappaB-Inducing Kinase