TY - GEN AU - Rontein,Denis AU - Onillon,Sandrine AU - Herbette,Gaëtan AU - Lesot,Agnes AU - Werck-Reichhart,Danièle AU - Sallaud,Christophe AU - Tissier,Alain TI - CYP725A4 from yew catalyzes complex structural rearrangement of taxa-4(5),11(12)-diene into the cyclic ether 5(12)-oxa-3(11)-cyclotaxane SN - 0021-9258 PY - 2008///0530 KW - Alkenes KW - metabolism KW - Antineoplastic Agents, Phytogenic KW - biosynthesis KW - Catalysis KW - Cytochrome P-450 Enzyme System KW - genetics KW - Diterpenes KW - Hydroxylation KW - Isomerases KW - Microsomes KW - enzymology KW - Oxidation-Reduction KW - Paclitaxel KW - Plant Proteins KW - Plants, Genetically Modified KW - Saccharomyces cerevisiae KW - Taxoids KW - Nicotiana N1 - Publication Type: Journal Article UR - https://doi.org/10.1074/jbc.M708950200 ER -