TY - GEN AU - Johannessen,Cory M AU - Johnson,Bryan W AU - Williams,Sybil M Genther AU - Chan,Annie W AU - Reczek,Elizabeth E AU - Lynch,Ryan C AU - Rioth,Matthew J AU - McClatchey,Andrea AU - Ryeom,Sandra AU - Cichowski,Karen TI - TORC1 is essential for NF1-associated malignancies SN - 0960-9822 PY - 2008///0327 KW - Animals KW - Cell Line KW - Cyclin D KW - Cyclins KW - genetics KW - Disease Models, Animal KW - Gene Expression Regulation KW - drug effects KW - Genes, Neurofibromatosis 1 KW - Hypoxia-Inducible Factor 1, alpha Subunit KW - Mice KW - Mice, Inbred C57BL KW - Mice, Transgenic KW - Neoplasms KW - Protein Kinase Inhibitors KW - pharmacology KW - Protein Kinases KW - metabolism KW - Proto-Oncogene Proteins c-akt KW - Sirolimus KW - TOR Serine-Threonine Kinases KW - Transcription Factors N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1016/j.cub.2007.11.066 ER -