Structure analysis of bone morphogenetic protein-2 type I receptor complexes reveals a mechanism of receptor inactivation in juvenile polyposis syndrome. [electronic resource]
- The Journal of biological chemistry Feb 2008
- 5876-87 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
0021-9258
10.1074/jbc.M706029200 doi
Adenomatous Polyposis Coli--genetics Adult Binding Sites--genetics Bone Morphogenetic Protein 2 Bone Morphogenetic Protein Receptors, Type I--chemistry Bone Morphogenetic Protein Receptors, Type II--chemistry Bone Morphogenetic Proteins--chemistry Colon--metabolism Embryonic Development--genetics Enterocytes--metabolism Epitopes--chemistry Homeostasis--genetics Humans Ligands Mutation Protein Binding--genetics Protein Structure, Quaternary--genetics Protein Structure, Tertiary--genetics Signal Transduction--genetics Structure-Activity Relationship Transforming Growth Factor beta--chemistry Tumor Suppressor Proteins--chemistry