Fang, Annie F

Significant decrease in nelfinavir systemic exposure after omeprazole coadministration in healthy subjects. [electronic resource] - Pharmacotherapy Jan 2008 - 42-50 p. digital

Publication Type: Journal Article; Randomized Controlled Trial

0277-0008

10.1592/phco.28.1.42 doi


Adolescent
Adult
Area Under Curve
Aryl Hydrocarbon Hydroxylases--antagonists & inhibitors
Chromatography, High Pressure Liquid
Cytochrome P-450 CYP2C19
Cytochrome P-450 CYP3A
Cytochrome P-450 CYP3A Inhibitors
Diarrhea--chemically induced
Dizziness--chemically induced
Drug Interactions
Female
Gastric Juice--drug effects
HIV Protease Inhibitors--adverse effects
Headache--chemically induced
Humans
Hydrogen-Ion Concentration--drug effects
Male
Metabolic Clearance Rate
Middle Aged
Mixed Function Oxygenases--antagonists & inhibitors
Nelfinavir--adverse effects
Omeprazole--adverse effects
Proton Pump Inhibitors--adverse effects
Syncope--chemically induced
Tablets