Fang, Annie F
Significant decrease in nelfinavir systemic exposure after omeprazole coadministration in healthy subjects. [electronic resource]
- Pharmacotherapy Jan 2008
- 42-50 p. digital
Publication Type: Journal Article; Randomized Controlled Trial
ISSN: 0277-0008
Standard No.: 10.1592/phco.28.1.42 doi
Subjects--Topical Terms: Adolescent Adult Area Under Curve Aryl Hydrocarbon Hydroxylases--antagonists & inhibitors Chromatography, High Pressure Liquid Cytochrome P-450 CYP2C19 Cytochrome P-450 CYP3A Cytochrome P-450 CYP3A Inhibitors Diarrhea--chemically induced Dizziness--chemically induced Drug Interactions Female Gastric Juice--drug effects HIV Protease Inhibitors--adverse effects Headache--chemically induced Humans Hydrogen-Ion Concentration--drug effects Male Metabolic Clearance Rate Middle Aged Mixed Function Oxygenases--antagonists & inhibitors Nelfinavir--adverse effects Omeprazole--adverse effects Proton Pump Inhibitors--adverse effects Syncope--chemically induced Tablets