TY  - GEN
AU  - Wang,Hongwei
AU  - Li,Hao
AU  - Moore,Linda B
AU  - Johnson,Michael D L
AU  - Maglich,Jodi M
AU  - Goodwin,Bryan
AU  - Ittoop,Olivia R R
AU  - Wisely,Bruce
AU  - Creech,Katrina
AU  - Parks,Derek J
AU  - Collins,Jon L
AU  - Willson,Timothy M
AU  - Kalpana,Ganjam V
AU  - Venkatesh,Madhukumar
AU  - Xie,Wen
AU  - Cho,Sool Y
AU  - Roboz,John
AU  - Redinbo,Matthew
AU  - Moore,John T
AU  - Mani,Sridhar
TI  - The phytoestrogen coumestrol is a naturally occurring antagonist of the human pregnane X receptor
SN  - 0888-8809
PY  - 2008///0721
KW  - Animals
KW  - Aryl Hydrocarbon Hydroxylases
KW  - genetics
KW  - Cell Line
KW  - Cells, Cultured
KW  - Constitutive Androstane Receptor
KW  - Coumestrol
KW  - chemistry
KW  - Cytochrome P-450 CYP2B6
KW  - Cytochrome P-450 CYP3A
KW  - Ethanol
KW  - analogs & derivatives
KW  - Female
KW  - Gene Expression
KW  - drug effects
KW  - Histone Acetyltransferases
KW  - Humans
KW  - Immunohistochemistry
KW  - Mass Spectrometry
KW  - Mice
KW  - Mice, Knockout
KW  - Mice, Transgenic
KW  - Microscopy, Confocal
KW  - Nuclear Receptor Coactivator 1
KW  - Oxidoreductases, N-Demethylating
KW  - Phytoestrogens
KW  - Pregnane X Receptor
KW  - Protein Binding
KW  - Receptors, Cytoplasmic and Nuclear
KW  - Receptors, Steroid
KW  - antagonists & inhibitors
KW  - Transcription Factors
KW  - Two-Hybrid System Techniques
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1210/me.2007-0218
ER  -