Wang, Hongwei

The phytoestrogen coumestrol is a naturally occurring antagonist of the human pregnane X receptor. [electronic resource] - Molecular endocrinology (Baltimore, Md.) Apr 2008 - 838-57 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0888-8809

10.1210/me.2007-0218 doi


Animals
Aryl Hydrocarbon Hydroxylases--genetics
Cell Line
Cells, Cultured
Constitutive Androstane Receptor
Coumestrol--chemistry
Cytochrome P-450 CYP2B6
Cytochrome P-450 CYP3A--genetics
Ethanol--analogs & derivatives
Female
Gene Expression--drug effects
Histone Acetyltransferases--genetics
Humans
Immunohistochemistry
Mass Spectrometry
Mice
Mice, Knockout
Mice, Transgenic
Microscopy, Confocal
Nuclear Receptor Coactivator 1
Oxidoreductases, N-Demethylating--genetics
Phytoestrogens--chemistry
Pregnane X Receptor
Protein Binding
Receptors, Cytoplasmic and Nuclear--genetics
Receptors, Steroid--antagonists & inhibitors
Transcription Factors--genetics
Two-Hybrid System Techniques