The cytotoxicity of eosinophil cationic protein/ribonuclease 3 on eukaryotic cell lines takes place through its aggregation on the cell membrane. [electronic resource]
- Cellular and molecular life sciences : CMLS Jan 2008
- 324-37 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1420-682X
10.1007/s00018-007-7499-7 doi
Calcium--metabolism Caspase Inhibitors Cell Cycle--drug effects Cell Death--drug effects Cell Line Cell Membrane--enzymology Cell Membrane Permeability--drug effects Eosinophil Cationic Protein--chemistry Eukaryotic Cells--cytology HL-60 Cells HeLa Cells Humans Intracellular Space--metabolism Lipid Bilayers--metabolism Microscopy, Confocal Phosphatidylserines--metabolism Protein Structure, Quaternary Protein Transport--drug effects RNA--metabolism Reactive Oxygen Species--metabolism Time Factors