TY - GEN AU - De La Fuente,Ricardo AU - Namkung,Wan AU - Mills,Aaron AU - Verkman,A S TI - Small-molecule screen identifies inhibitors of a human intestinal calcium-activated chloride channel SN - 1521-0111 PY - 2008///0407 KW - Adenosine Triphosphate KW - antagonists & inhibitors KW - Calcium KW - analysis KW - Carbachol KW - Chloride Channels KW - Chlorides KW - metabolism KW - Dose-Response Relationship, Drug KW - Drug Evaluation, Preclinical KW - methods KW - Fluorescent Dyes KW - Fura-2 KW - Genetic Vectors KW - HT29 Cells KW - Humans KW - Inhibitory Concentration 50 KW - Intestinal Mucosa KW - Intestines KW - drug effects KW - Ion Channel Gating KW - Kinetics KW - Lentivirus KW - genetics KW - Models, Biological KW - Molecular Structure KW - Patch-Clamp Techniques KW - Reproducibility of Results KW - Structure-Activity Relationship N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural UR - https://doi.org/10.1124/mol.107.043208 ER -