TY  - GEN
AU  - Tsutsumi,R
AU  - Ito,H
AU  - Hiramitsu,T
AU  - Nishitani,K
AU  - Akiyoshi,M
AU  - Kitaori,T
AU  - Yasuda,T
AU  - Nakamura,T
TI  - Celecoxib inhibits production of MMP and NO via down-regulation of NF-kappaB and JNK in a PGE2 independent manner in human articular chondrocytes
SN  - 0172-8172
PY  - 2008///1028
KW  - Aged
KW  - Cartilage, Articular
KW  - cytology
KW  - Celecoxib
KW  - Cells, Cultured
KW  - Chondrocytes
KW  - drug effects
KW  - Cyclooxygenase 2
KW  - metabolism
KW  - Cyclooxygenase Inhibitors
KW  - pharmacology
KW  - Dinoprostone
KW  - Down-Regulation
KW  - Enzyme Activation
KW  - Humans
KW  - Interleukin-1beta
KW  - JNK Mitogen-Activated Protein Kinases
KW  - Matrix Metalloproteinase 1
KW  - biosynthesis
KW  - Matrix Metalloproteinase 3
KW  - Matrix Metalloproteinases
KW  - NF-kappa B
KW  - Nitric Oxide
KW  - Nitric Oxide Synthase Type II
KW  - Phosphorylation
KW  - Pyrazoles
KW  - Sulfonamides
N1  - Publication Type: Journal Article
UR  - https://doi.org/10.1007/s00296-007-0511-6
ER  -