Ageing-exaggerated proliferation of vascular smooth muscle cells is related to attenuation of Jagged1 expression in endothelial cells. [electronic resource]
- Cardiovascular research Mar 2008
- 800-8 p. digital
Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
0008-6363
10.1093/cvr/cvm105 doi
Age Factors Aging--metabolism Animals Aorta, Thoracic--injuries Aortic Diseases--metabolism Calcium-Binding Proteins--genetics Cell Movement Cell Proliferation Cells, Cultured Coculture Techniques Disease Models, Animal Down-Regulation Endothelial Cells--metabolism Hyperplasia Intercellular Signaling Peptides and Proteins--genetics Jagged-1 Protein Male Membrane Proteins--genetics Muscle, Smooth, Vascular--metabolism Myocytes, Smooth Muscle--metabolism Paracrine Communication Platelet-Derived Growth Factor--metabolism Proliferating Cell Nuclear Antigen--metabolism RNA Interference Rats Rats, Sprague-Dawley Serrate-Jagged Proteins Time Factors