TY - GEN AU - Iwamoto,Marian AU - Kassahun,Kelem AU - Troyer,Matthew D AU - Hanley,William D AU - Lu,Ping AU - Rhoton,Alisha AU - Petry,Amelia S AU - Ghosh,Kalyan AU - Mangin,Eric AU - DeNoia,Emanuel P AU - Wenning,Larissa A AU - Stone,Julie A AU - Gottesdiener,Keith M AU - Wagner,John A TI - Lack of a pharmacokinetic effect of raltegravir on midazolam: in vitro/in vivo correlation SN - 0091-2700 PY - 2008///0519 KW - Area Under Curve KW - Cells, Cultured KW - Chromatography, Liquid KW - Cross-Over Studies KW - Cytochrome P-450 CYP3A KW - genetics KW - Dose-Response Relationship, Drug KW - Drug Interactions KW - Female KW - HIV Integrase Inhibitors KW - pharmacology KW - Half-Life KW - Hepatocytes KW - cytology KW - Humans KW - Male KW - Mass Spectrometry KW - Metabolic Clearance Rate KW - Microsomes, Liver KW - drug effects KW - Midazolam KW - administration & dosage KW - Organic Chemicals KW - Pyrrolidinones KW - Raltegravir Potassium KW - Reverse Transcriptase Polymerase Chain Reaction N1 - Publication Type: Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1177/0091270007310382 ER -