TY - GEN AU - Kumar,Ajay AU - Malik,Fayaz AU - Bhushan,Shashi AU - Sethi,Vijay K AU - Shahi,Ashok K AU - Kaur,Jagdeep AU - Taneja,Subhash C AU - Qazi,Ghulam N AU - Singh,Jaswant TI - An essential oil and its major constituent isointermedeol induce apoptosis by increased expression of mitochondrial cytochrome c and apical death receptors in human leukaemia HL-60 cells SN - 0009-2797 PY - 2008///0519 KW - Apoptosis KW - drug effects KW - Caspase 8 KW - biosynthesis KW - Caspase 9 KW - Cell Cycle KW - Cell Proliferation KW - Cymbopogon KW - chemistry KW - Cytochromes c KW - DNA KW - Dose-Response Relationship, Drug KW - Drug Screening Assays, Antitumor KW - HL-60 Cells KW - Humans KW - Leukemia, Promyelocytic, Acute KW - drug therapy KW - Mitochondria KW - Molecular Conformation KW - NF-kappa B KW - Oils, Volatile KW - Reactive Oxygen Species KW - metabolism KW - Receptors, TNF-Related Apoptosis-Inducing Ligand KW - Receptors, Tumor Necrosis Factor KW - Receptors, Tumor Necrosis Factor, Type I KW - Sesquiterpenes KW - Signal Transduction KW - Tumor Cells, Cultured KW - bcl-2-Associated X Protein N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1016/j.cbi.2007.10.003 ER -