TY - GEN AU - El-Deiry,Wafik S TI - Targeting mutant p53 shows promise for sunscreens and skin cancer SN - 0021-9738 PY - 2008///0212 KW - Animals KW - Apoptosis KW - drug effects KW - Caspase 3 KW - genetics KW - Cell Line, Tumor KW - Cell Transformation, Neoplastic KW - Cyclin D KW - Cyclins KW - Cytochromes c KW - Environmental Exposure KW - adverse effects KW - Female KW - Humans KW - Male KW - Mice KW - Mice, Hairless KW - Mitochondria KW - Mitochondrial Membrane Transport Proteins KW - antagonists & inhibitors KW - Mitochondrial Permeability Transition Pore KW - Mutation KW - Neoplasms, Radiation-Induced KW - drug therapy KW - Poly(ADP-ribose) Polymerases KW - Proliferating Cell Nuclear Antigen KW - Protein Transport KW - Pyrimidines KW - pharmacology KW - Skin Neoplasms KW - Tumor Suppressor Protein p53 KW - Ultraviolet Rays KW - bcl-X Protein N1 - Publication Type: Journal Article; Comment UR - https://doi.org/10.1172/JCI34251 ER -