Biggadike, Keith <br/><br/>
Nonsteroidal glucocorticoid agonists: tetrahydronaphthalenes with alternative steroidal A-ring mimetics possessing dissociated (transrepression/transactivation) efficacy selectivity.  [electronic resource] 

 -  Journal of medicinal chemistry  Dec 2007 
 - 6519-34 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>0022-2623 
<br/><br/><label>Standard No.: </label>10.1021/jm070778w  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Anti-Inflammatory Agents, Non-Steroidal--chemical synthesis<br/>Binding Sites<br/>Cell Line<br/>Drug Partial Agonism<br/>Humans<br/>Mammary Tumor Virus, Mouse--genetics<br/>Models, Molecular<br/>Molecular Mimicry<br/>NF-kappa B--genetics<br/>Receptors, Glucocorticoid--agonists<br/>Stereoisomerism<br/>Structure-Activity Relationship<br/>Tetrahydronaphthalenes--chemical synthesis<br/>Transcription, Genetic--drug effects<br/>Transcriptional Activation--drug effects