TY - GEN AU - Shing,Danielle C AU - Trubia,Maurizio AU - Marchesi,Francesco AU - Radaelli,Enrico AU - Belloni,Elena AU - Tapinassi,Cinzia AU - Scanziani,Eugenio AU - Mecucci,Cristina AU - Crescenzi,Barbara AU - Lahortiga,Idoya AU - Odero,Maria D AU - Zardo,Giuseppe AU - Gruszka,Alicja AU - Minucci,Saverio AU - Di Fiore,Pier Paolo AU - Pelicci,Pier Giuseppe TI - Overexpression of sPRDM16 coupled with loss of p53 induces myeloid leukemias in mice SN - 0021-9738 PY - 2008///0212 KW - Animals KW - Bone Marrow KW - metabolism KW - Cell Differentiation KW - genetics KW - Cell Transformation, Neoplastic KW - Cellular Senescence KW - DNA-Binding Proteins KW - biosynthesis KW - Gene Expression Regulation, Leukemic KW - Hematopoietic Stem Cells KW - Humans KW - Leukemia, Myeloid, Acute KW - Mice KW - Mice, Knockout KW - Neoplastic Stem Cells KW - Nuclear Proteins KW - Nucleophosmin KW - Protein Isoforms KW - Protein Structure, Tertiary KW - Transcription Factors KW - Translocation, Genetic KW - Tumor Suppressor Protein p53 N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1172/JCI32390 ER -