Martin, P <br/><br/>
Comparison of the induction profile for drug disposition proteins by typical nuclear receptor activators in human hepatic and intestinal cells.  [electronic resource] 

 -  British journal of pharmacology  Feb 2008 
 - 805-19 p.  digital 
<br/><br/> Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>0007-1188 
<br/><br/><label>Standard No.: </label>10.1038/sj.bjp.0707601  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>ATP Binding Cassette Transporter, Subfamily B<br/>ATP Binding Cassette Transporter, Subfamily B, Member 1--biosynthesis<br/>ATP-Binding Cassette Transporters--biosynthesis<br/>Aryl Hydrocarbon Hydroxylases--biosynthesis<br/>Caco-2 Cells<br/>Cell Culture Techniques<br/>Cells, Cultured<br/>Chenodeoxycholic Acid--pharmacology<br/>Constitutive Androstane Receptor<br/>Cytochrome P-450 CYP2B6<br/>Cytochrome P-450 CYP3A--biosynthesis<br/>Cytochrome P-450 Enzyme System--biosynthesis<br/>DNA-Binding Proteins--agonists<br/>Dexamethasone--pharmacology<br/>Dose-Response Relationship, Drug<br/>Enzyme Induction<br/>Epithelial Cells--drug effects<br/>Hepatocytes--drug effects<br/>Humans<br/>Intestinal Mucosa--drug effects<br/>Membrane Transport Proteins--biosynthesis<br/>Multidrug Resistance-Associated Protein 2<br/>Multidrug Resistance-Associated Proteins--biosynthesis<br/>Oxidoreductases, N-Demethylating--biosynthesis<br/>Phenobarbital--pharmacology<br/>Pregnane X Receptor<br/>Pregnenolone Carbonitrile--pharmacology<br/>RNA, Messenger--biosynthesis<br/>Receptors, Cytoplasmic and Nuclear--agonists<br/>Receptors, Steroid--agonists<br/>Research Design<br/>Rifampin--pharmacology<br/>Transcription Factors--agonists<br/>Up-Regulation