TY - GEN AU - Higgins,Larry G AU - Cavin,Christophe AU - Itoh,Ken AU - Yamamoto,Masayuki AU - Hayes,John D TI - Induction of cancer chemopreventive enzymes by coffee is mediated by transcription factor Nrf2. Evidence that the coffee-specific diterpenes cafestol and kahweol confer protection against acrolein SN - 0041-008X PY - 2008///0318 KW - Acrolein KW - chemistry KW - Administration, Oral KW - Animals KW - Anticarcinogenic Agents KW - Coffee KW - Diet KW - Diterpenes KW - Dose-Response Relationship, Drug KW - Enzyme Induction KW - drug effects KW - Gene Expression Regulation, Enzymologic KW - Gene Silencing KW - Glutathione Transferase KW - genetics KW - Intestine, Small KW - Isoenzymes KW - Liver KW - Male KW - Mice KW - Mice, Inbred C57BL KW - Mice, Knockout KW - NAD(P)H Dehydrogenase (Quinone) KW - NADPH Dehydrogenase KW - NF-E2-Related Factor 2 KW - RNA, Messenger KW - metabolism KW - Response Elements KW - Transcriptional Activation KW - Up-Regulation N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1016/j.taap.2007.09.018 ER -