TY - GEN AU - Ohta,Akio AU - Lukashev,Dmitriy AU - Jackson,Edwin K AU - Fredholm,Bertil B AU - Sitkovsky,Michail TI - 1,3,7-trimethylxanthine (caffeine) may exacerbate acute inflammatory liver injury by weakening the physiological immunosuppressive mechanism SN - 0022-1767 PY - 2008///0205 KW - ADP Ribose Transferases KW - Acute Disease KW - Adenosine A2 Receptor Antagonists KW - Animals KW - Bacterial Toxins KW - Caffeine KW - blood KW - Chemical and Drug Induced Liver Injury KW - immunology KW - Disease Models, Animal KW - Dose-Response Relationship, Drug KW - Exotoxins KW - Female KW - Liver KW - drug effects KW - Mice KW - Mice, Inbred C57BL KW - Mice, Knockout KW - Phosphodiesterase Inhibitors KW - Receptor, Adenosine A2A KW - genetics KW - Virulence Factors KW - Pseudomonas aeruginosa Exotoxin A N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural UR - https://doi.org/10.4049/jimmunol.179.11.7431 ER -