TY  - GEN
AU  - Krajewski,Wojciech W
AU  - Collins,Ruairi
AU  - Holmberg-Schiavone,Lovisa
AU  - Jones,T Alwyn
AU  - Karlberg,Tobias
AU  - Mowbray,Sherry L
TI  - Crystal structures of mammalian glutamine synthetases illustrate substrate-induced conformational changes and provide opportunities for drug and herbicide design
SN  - 1089-8638
PY  - 2008///0108
KW  - Adenosine Triphosphate
KW  - metabolism
KW  - Amino Acid Sequence
KW  - Animals
KW  - Apoenzymes
KW  - chemistry
KW  - Binding Sites
KW  - Catalytic Domain
KW  - Cloning, Molecular
KW  - Crystallography, X-Ray
KW  - Dogs
KW  - Drug Design
KW  - Drug Interactions
KW  - Glutamate-Ammonia Ligase
KW  - Herbicides
KW  - chemical synthesis
KW  - Humans
KW  - Hydrogen Bonding
KW  - Kinetics
KW  - Ligands
KW  - Magnesium
KW  - Models, Chemical
KW  - Models, Molecular
KW  - Molecular Sequence Data
KW  - Pharmaceutical Preparations
KW  - Protein Binding
KW  - Protein Conformation
KW  - Protein Structure, Tertiary
KW  - Sequence Homology, Amino Acid
KW  - Substrate Specificity
KW  - Temperature
N1  - Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1016/j.jmb.2007.10.029
ER  -