TY - GEN AU - Kondo,Asuka AU - Hirayama,Naoki AU - Sugito,Yasuko AU - Shono,Michihiro AU - Tanaka,Toshiaki AU - Kitamura,Naomi TI - Coupling of Grb2 to Gab1 mediates hepatocyte growth factor-induced high intensity ERK signal required for inhibition of HepG2 hepatoma cell proliferation SN - 0021-9258 PY - 2008///0214 KW - Adaptor Proteins, Signal Transducing KW - metabolism KW - Animals KW - COS Cells KW - Carcinoma, Hepatocellular KW - enzymology KW - Cell Proliferation KW - drug effects KW - Chlorocebus aethiops KW - Clone Cells KW - Cyclin-Dependent Kinase Inhibitor p16 KW - Enzyme Activation KW - Extracellular Signal-Regulated MAP Kinases KW - GRB2 Adaptor Protein KW - Hepatocyte Growth Factor KW - pharmacology KW - Humans KW - Liver Neoplasms KW - MAP Kinase Signaling System KW - Mutant Proteins KW - Phosphorylation KW - Protein Binding KW - Proto-Oncogene Proteins c-met KW - Rats KW - Recombinant Proteins KW - Up-Regulation N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1074/jbc.M704999200 ER -