Kondo, Asuka <br/><br/>
Coupling of Grb2 to Gab1 mediates hepatocyte growth factor-induced high intensity ERK signal required for inhibition of HepG2 hepatoma cell proliferation.  [electronic resource] 

 -  The Journal of biological chemistry  Jan 2008 
 - 1428-1436 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>0021-9258 
<br/><br/><label>Standard No.: </label>10.1074/jbc.M704999200  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Adaptor Proteins, Signal Transducing--metabolism<br/>Animals<br/>COS Cells<br/>Carcinoma, Hepatocellular--enzymology<br/>Cell Proliferation--drug effects<br/>Chlorocebus aethiops<br/>Clone Cells<br/>Cyclin-Dependent Kinase Inhibitor p16--metabolism<br/>Enzyme Activation--drug effects<br/>Extracellular Signal-Regulated MAP Kinases--metabolism<br/>GRB2 Adaptor Protein--metabolism<br/>Hepatocyte Growth Factor--pharmacology<br/>Humans<br/>Liver Neoplasms--enzymology<br/>MAP Kinase Signaling System--drug effects<br/>Mutant Proteins--metabolism<br/>Phosphorylation--drug effects<br/>Protein Binding--drug effects<br/>Proto-Oncogene Proteins c-met--metabolism<br/>Rats<br/>Recombinant Proteins--metabolism<br/>Up-Regulation--drug effects