TY - GEN AU - Le Bras,Gaëlle AU - Radanyi,Christine AU - Peyrat,Jean-François AU - Brion,Jean-Daniel AU - Alami,Mouâd AU - Marsaud,Véronique AU - Stella,Barbara AU - Renoir,Jack-Michel TI - New novobiocin analogues as antiproliferative agents in breast cancer cells and potential inhibitors of heat shock protein 90 SN - 0022-2623 PY - 2008///0227 KW - Antineoplastic Agents KW - chemical synthesis KW - Apoptosis KW - Breast Neoplasms KW - Caspases KW - metabolism KW - Cell Line, Tumor KW - Cell Proliferation KW - drug effects KW - Cyclin-Dependent Kinase 4 KW - Drug Screening Assays, Antitumor KW - Estradiol KW - pharmacology KW - Estrogen Receptor alpha KW - Female KW - Flow Cytometry KW - HSP90 Heat-Shock Proteins KW - antagonists & inhibitors KW - Humans KW - Novobiocin KW - analogs & derivatives KW - Proteasome Endopeptidase Complex KW - Proto-Oncogene Proteins c-raf KW - Receptor, ErbB-2 KW - Signal Transduction KW - Structure-Activity Relationship KW - Transcription, Genetic N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1021/jm0707774 ER -