Srivastava, Brijesh Kumar

Diaryl dihydropyrazole-3-carboxamides with significant in vivo antiobesity activity related to CB1 receptor antagonism: synthesis, biological evaluation, and molecular modeling in the homology model. [electronic resource] - Journal of medicinal chemistry Nov 2007 - 5951-66 p. digital

Publication Type: Journal Article

0022-2623

10.1021/jm061490u doi


Amides--chemical synthesis
Animals
Anti-Obesity Agents--chemical synthesis
Appetite Depressants--chemical synthesis
Body Weight--drug effects
Female
Models, Molecular
Morpholines--chemical synthesis
Piperidines--chemistry
Pyrazoles--chemical synthesis
Rats
Rats, Zucker
Receptor, Cannabinoid, CB1--antagonists & inhibitors
Rimonabant
Stereoisomerism
Structure-Activity Relationship
Sulfonamides--chemistry