Cavin, C

Induction of Nrf2-mediated cellular defenses and alteration of phase I activities as mechanisms of chemoprotective effects of coffee in the liver. [electronic resource] - Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association Apr 2008 - 1239-48 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0278-6915

10.1016/j.fct.2007.09.099 doi


Aflatoxin B1--toxicity
Animals
Anticarcinogenic Agents--pharmacology
Antioxidants--metabolism
Blotting, Western
Carcinogens--toxicity
Coffee--chemistry
Cytochrome P-450 CYP1A1--metabolism
Cytochrome P-450 CYP1A2--metabolism
Cytochrome P-450 CYP3A
Cytochrome P-450 Enzyme System--metabolism
Dose-Response Relationship, Drug
Genes, Reporter
Glutathione--metabolism
Glutathione Transferase--metabolism
Hepatocytes--drug effects
Humans
Liver Neoplasms, Experimental--chemically induced
Luciferases--metabolism
Male
NF-E2-Related Factor 2--biosynthesis
Rats
Rats, Sprague-Dawley
Regulatory Elements, Transcriptional
Reverse Transcriptase Polymerase Chain Reaction