TY - GEN AU - Ding,Keyue AU - McDonough,Samantha J AU - Kullo,Iftikhar J TI - Evidence for positive selection in the C-terminal domain of the cholesterol metabolism gene PCSK9 based on phylogenetic analysis in 14 primate species SN - 1932-6203 PY - 2008///0715 KW - Amino Acid Sequence KW - Animals KW - Cholesterol KW - metabolism KW - Cholesterol, LDL KW - Evolution, Molecular KW - Humans KW - Models, Biological KW - Molecular Sequence Data KW - Mutation KW - Primates KW - Proprotein Convertase 9 KW - Proprotein Convertases KW - Protein Structure, Tertiary KW - Receptors, LDL KW - Sequence Homology, Amino Acid KW - Serine Endopeptidases KW - chemistry KW - Species Specificity N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1371/journal.pone.0001098 ER -