Furber, Mark <br/><br/>
Discovery of potent and selective adamantane-based small-molecule P2X(7) receptor antagonists/interleukin-1beta inhibitors.  [electronic resource] 

 -  Journal of medicinal chemistry  Nov 2007 
 - 5882-5 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>0022-2623 
<br/><br/><label>Standard No.: </label>10.1021/jm700949w  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Adamantane--analogs & derivatives<br/>Animals<br/>Benzamides--chemical synthesis<br/>Blood Proteins--metabolism<br/>Crystallography, X-Ray<br/>Humans<br/>In Vitro Techniques<br/>Interleukin-1beta--antagonists & inhibitors<br/>Molecular Conformation<br/>Monocytes--metabolism<br/>Protein Binding<br/>Purinergic P2 Receptor Antagonists<br/>Rats<br/>Receptors, Purinergic P2X7<br/>Structure-Activity Relationship