Production of P-glycoprotein from the MDR1 upstream promoter is insufficient to affect the response to first-line chemotherapy in advanced breast cancer. [electronic resource]
- International journal of cancer Mar 2008
- 1058-67 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1097-0215
10.1002/ijc.23149 doi
ATP Binding Cassette Transporter, Subfamily B, Member 1--genetics Adult Antineoplastic Agents--therapeutic use Breast Neoplasms--drug therapy Cloning, Molecular Drug Resistance, Multiple--genetics Electrophoretic Mobility Shift Assay Female Genes, MDR Humans Middle Aged Promoter Regions, Genetic--genetics RNA, Messenger--analysis Reverse Transcriptase Polymerase Chain Reaction