TY  - GEN
AU  - Tao,Zhi-Fu
AU  - Chen,Zehan
AU  - Bui,Mai-Ha
AU  - Kovar,Peter
AU  - Johnson,Eric
AU  - Bouska,Jennifer
AU  - Zhang,Haiying
AU  - Rosenberg,Saul
AU  - Sowin,Thomas
AU  - Lin,Nan-Horng
TI  - Macrocyclic ureas as potent and selective Chk1 inhibitors: an improved synthesis, kinome profiling, structure-activity relationships, and preliminary pharmacokinetics
SN  - 1464-3405
PY  - 2008///0303
KW  - Animals
KW  - Catalysis
KW  - Checkpoint Kinase 1
KW  - HeLa Cells
KW  - Humans
KW  - Macrocyclic Compounds
KW  - chemical synthesis
KW  - Mice
KW  - Protein Kinase Inhibitors
KW  - Protein Kinases
KW  - pharmacokinetics
KW  - Structure-Activity Relationship
KW  - Urea
N1  - Publication Type: Comparative Study; Journal Article
UR  - https://doi.org/10.1016/j.bmcl.2007.09.063
ER  -