TY  - GEN
AU  - Wu,Chengbin
AU  - Ying,Hua
AU  - Grinnell,Christine
AU  - Bryant,Shaughn
AU  - Miller,Renee
AU  - Clabbers,Anca
AU  - Bose,Sahana
AU  - McCarthy,Donna
AU  - Zhu,Rong-Rong
AU  - Santora,Ling
AU  - Davis-Taber,Rachel
AU  - Kunes,Yune
AU  - Fung,Emma
AU  - Schwartz,Annette
AU  - Sakorafas,Paul
AU  - Gu,Jijie
AU  - Tarcsa,Edit
AU  - Murtaza,Anwar
AU  - Ghayur,Tariq
TI  - Simultaneous targeting of multiple disease mediators by a dual-variable-domain immunoglobulin
SN  - 1087-0156
PY  - 2008///0228
KW  - Animals
KW  - Antibodies, Bispecific
KW  - biosynthesis
KW  - Antibodies, Monoclonal
KW  - Arthritis, Experimental
KW  - drug therapy
KW  - CHO Cells
KW  - Cricetinae
KW  - Cricetulus
KW  - Disease Models, Animal
KW  - Humans
KW  - Immunoglobulin Variable Region
KW  - Interleukin-12
KW  - antagonists & inhibitors
KW  - Interleukin-18
KW  - Mice
KW  - Protein Engineering
KW  - Protein Structure, Tertiary
KW  - Rats
N1  - Publication Type: Journal Article
UR  - https://doi.org/10.1038/nbt1345
ER  -