Wu, Chengbin <br/><br/>
Simultaneous targeting of multiple disease mediators by a dual-variable-domain immunoglobulin.  [electronic resource] 

 -  Nature biotechnology  Nov 2007 
 - 1290-7 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>1087-0156 
<br/><br/><label>Standard No.: </label>10.1038/nbt1345  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Antibodies, Bispecific--biosynthesis<br/>Antibodies, Monoclonal--biosynthesis<br/>Arthritis, Experimental--drug therapy<br/>CHO Cells<br/>Cricetinae<br/>Cricetulus<br/>Disease Models, Animal<br/>Humans<br/>Immunoglobulin Variable Region--biosynthesis<br/>Interleukin-12--antagonists & inhibitors<br/>Interleukin-18--antagonists & inhibitors<br/>Mice<br/>Protein Engineering<br/>Protein Structure, Tertiary<br/>Rats