TY  - GEN
AU  - Vlugt-Wensink,K D F
AU  - de Vrueh,R
AU  - Gresnigt,M G
AU  - Hoogerbrugge,C M
AU  - van Buul-Offers,S C
AU  - de Leede,L G J
AU  - Sterkman,L G W
AU  - Crommelin,D J A
AU  - Hennink,W E
AU  - Verrijk,R
TI  - Preclinical and clinical in vitro in vivo correlation of an hGH dextran microsphere formulation
SN  - 0724-8741
PY  - 2007///1220
KW  - Aged
KW  - Animals
KW  - Biomarkers
KW  - blood
KW  - Body Size
KW  - drug effects
KW  - Body Weight
KW  - Chemistry, Pharmaceutical
KW  - Delayed-Action Preparations
KW  - Dextrans
KW  - chemistry
KW  - Disease Models, Animal
KW  - Drug Carriers
KW  - Drug Compounding
KW  - Dwarfism
KW  - drug therapy
KW  - Human Growth Hormone
KW  - administration & dosage
KW  - Humans
KW  - Injections, Subcutaneous
KW  - Insulin-Like Growth Factor Binding Protein 3
KW  - Insulin-Like Growth Factor Binding Proteins
KW  - Insulin-Like Growth Factor I
KW  - metabolism
KW  - Male
KW  - Methacrylates
KW  - Mice
KW  - Mice, Mutant Strains
KW  - Microspheres
KW  - Middle Aged
KW  - Models, Biological
KW  - Particle Size
KW  - Solubility
KW  - Transcription Factor Pit-1
KW  - deficiency
N1  - Publication Type: Clinical Trial; Journal Article
UR  - https://doi.org/10.1007/s11095-007-9433-y
ER  -