The short hairpin RNA driven by polymerase II suppresses both wild-type and lamivudine-resistant hepatitis B virus strains. [electronic resource]
- Antiviral therapy 2007
- 865-76 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1359-6535
Animals Antiviral Agents--pharmacology Cell Line, Tumor DNA, Viral Drug Resistance, Viral Gene Expression Regulation, Viral Genetic Vectors Hepatitis B Surface Antigens--isolation & purification Hepatitis B virus--drug effects Hepatitis B, Chronic--metabolism Humans Lamivudine--pharmacology Liver--cytology Mice Mice, Inbred BALB C Mice, Transgenic RNA Interference RNA Polymerase II--metabolism RNA, Messenger RNA, Small Interfering--therapeutic use