Cortez, Dolores M

IL-17 stimulates MMP-1 expression in primary human cardiac fibroblasts via p38 MAPK- and ERK1/2-dependent C/EBP-beta , NF-kappaB, and AP-1 activation. [electronic resource] - American journal of physiology. Heart and circulatory physiology Dec 2007 - H3356-65 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural

0363-6135

10.1152/ajpheart.00928.2007 doi


CCAAT-Enhancer-Binding Protein-beta--genetics
Cell Movement
Cells, Cultured
Enzyme Induction
Extracellular Signal-Regulated MAP Kinases--antagonists & inhibitors
Fibroblasts--drug effects
Genes, Reporter
Humans
Interleukin-17--metabolism
Matrix Metalloproteinase 1--biosynthesis
Matrix Metalloproteinase 13--biosynthesis
Matrix Metalloproteinase 2--biosynthesis
Matrix Metalloproteinase 3--biosynthesis
Matrix Metalloproteinase 9--biosynthesis
Matrix Metalloproteinase Inhibitors
Mitogen-Activated Protein Kinase 1--metabolism
Mitogen-Activated Protein Kinase 3--metabolism
Myocardium--enzymology
NF-kappa B--genetics
Oligonucleotides, Antisense--metabolism
Promoter Regions, Genetic
Protease Inhibitors--pharmacology
Protein Kinase Inhibitors--pharmacology
RNA Interference
RNA, Messenger--biosynthesis
RNA, Small Interfering--metabolism
Recombinant Proteins--metabolism
Signal Transduction
Tissue Inhibitor of Metalloproteinase-1--biosynthesis
Transcription Factor AP-1--metabolism
Transcription, Genetic
Transfection
p38 Mitogen-Activated Protein Kinases--antagonists & inhibitors