TY - GEN AU - Vanwolleghem,Thomas AU - Meuleman,Philip AU - Libbrecht,Louis AU - Roskams,Tania AU - De Vos,Rita AU - Leroux-Roels,Geert TI - Ultra-rapid cardiotoxicity of the hepatitis C virus protease inhibitor BILN 2061 in the urokinase-type plasminogen activator mouse SN - 0016-5085 PY - 2007///1025 KW - Administration, Oral KW - Animals KW - Antiviral Agents KW - administration & dosage KW - Carbamates KW - Drug Evaluation, Preclinical KW - methods KW - Heart Diseases KW - chemically induced KW - Hepacivirus KW - drug effects KW - Hepatitis C KW - drug therapy KW - Humans KW - Liver KW - metabolism KW - Liver Transplantation KW - Macrocyclic Compounds KW - Mice KW - Mice, SCID KW - Mice, Transgenic KW - Mitochondria, Heart KW - Mitochondrial Swelling KW - Models, Animal KW - Myocytes, Cardiac KW - Protease Inhibitors KW - Quinolines KW - Thiazoles KW - Time Factors KW - Transplantation, Heterologous KW - Urokinase-Type Plasminogen Activator KW - blood KW - Viral Load KW - Viral Nonstructural Proteins KW - antagonists & inhibitors N1 - Publication Type: Evaluation Study; Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1053/j.gastro.2007.07.007 ER -