Vanwolleghem, Thomas <br/><br/>
Ultra-rapid cardiotoxicity of the hepatitis C virus protease inhibitor BILN 2061 in the urokinase-type plasminogen activator mouse.  [electronic resource] 

 -  Gastroenterology  Oct 2007 
 - 1144-55 p.  digital 
<br/><br/> Publication Type: Evaluation Study; Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>0016-5085 
<br/><br/><label>Standard No.: </label>10.1053/j.gastro.2007.07.007  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Administration, Oral<br/>Animals<br/>Antiviral Agents--administration & dosage<br/>Carbamates--administration & dosage<br/>Drug Evaluation, Preclinical--methods<br/>Heart Diseases--chemically induced<br/>Hepacivirus--drug effects<br/>Hepatitis C--drug therapy<br/>Humans<br/>Liver--metabolism<br/>Liver Transplantation<br/>Macrocyclic Compounds--administration & dosage<br/>Mice<br/>Mice, SCID<br/>Mice, Transgenic<br/>Mitochondria, Heart--drug effects<br/>Mitochondrial Swelling--drug effects<br/>Models, Animal<br/>Myocytes, Cardiac--drug effects<br/>Protease Inhibitors--administration & dosage<br/>Quinolines--administration & dosage<br/>Thiazoles--administration & dosage<br/>Time Factors<br/>Transplantation, Heterologous<br/>Urokinase-Type Plasminogen Activator--blood<br/>Viral Load<br/>Viral Nonstructural Proteins--antagonists & inhibitors