Inducible nitric oxide synthase and cyclooxygenase-2 participate in anti-inflammatory and analgesic effects of the natural marine compound lemnalol from Formosan soft coral Lemnalia cervicorni. [electronic resource]
- European journal of pharmacology Jan 2008
- 323-31 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
0014-2999
10.1016/j.ejphar.2007.08.048 doi
Analgesics--administration & dosage Animals Anthozoa--chemistry Anti-Inflammatory Agents--administration & dosage Carrageenan Cell Line Cyclooxygenase 2--metabolism Disease Models, Animal Dose-Response Relationship, Drug Hot Temperature Hyperalgesia--etiology Immunohistochemistry Inflammation--chemically induced Injections, Spinal Lipopolysaccharides--pharmacology Macrophages--drug effects Male Mice Neutrophil Infiltration--drug effects Nitric Oxide Synthase Type II--metabolism Pain Measurement Pain Threshold--drug effects Rats Rats, Wistar Sesquiterpenes--administration & dosage Time Factors