TY  - GEN
AU  - Peng,Hongjun
AU  - Sohara,Yasuyoshi
AU  - Moats,Rex A
AU  - Nelson,Marvin D
AU  - Groshen,Susan G
AU  - Ye,Wei
AU  - Reynolds,C Patrick
AU  - DeClerck,Yves A
TI  - The activity of zoledronic Acid on neuroblastoma bone metastasis involves inhibition of osteoclasts and tumor cell survival and proliferation
SN  - 0008-5472
PY  - 2007///1031
KW  - Animals
KW  - Antineoplastic Combined Chemotherapy Protocols
KW  - pharmacology
KW  - Apoptosis
KW  - drug effects
KW  - Bone Density Conservation Agents
KW  - Bone Neoplasms
KW  - metabolism
KW  - Caspase 3
KW  - Cell Growth Processes
KW  - Cell Survival
KW  - Cyclophosphamide
KW  - administration & dosage
KW  - Diphosphonates
KW  - Enzyme Activation
KW  - Humans
KW  - Imidazoles
KW  - Mice
KW  - Mice, Inbred BALB C
KW  - Mitogen-Activated Protein Kinase 1
KW  - antagonists & inhibitors
KW  - Mitogen-Activated Protein Kinase 3
KW  - Neuroblastoma
KW  - drug therapy
KW  - Osteoclasts
KW  - Proto-Oncogene Proteins c-akt
KW  - Proto-Oncogene Proteins c-bcl-2
KW  - Topotecan
KW  - Xenograft Model Antitumor Assays
KW  - Zoledronic Acid
KW  - ras Proteins
N1  - Publication Type: Journal Article; Research Support, N.I.H., Extramural
UR  - https://doi.org/10.1158/0008-5472.CAN-06-4508
ER  -