Peng, Hongjun <br/><br/>
The activity of zoledronic Acid on neuroblastoma bone metastasis involves inhibition of osteoclasts and tumor cell survival and proliferation.  [electronic resource] 

 -  Cancer research  Oct 2007 
 - 9346-55 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, N.I.H., Extramural 
<br/><br/><label>ISSN: </label>0008-5472 
<br/><br/><label>Standard No.: </label>10.1158/0008-5472.CAN-06-4508  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Antineoplastic Combined Chemotherapy Protocols--pharmacology<br/>Apoptosis--drug effects<br/>Bone Density Conservation Agents--pharmacology<br/>Bone Neoplasms--metabolism<br/>Caspase 3--metabolism<br/>Cell Growth Processes--drug effects<br/>Cell Survival--drug effects<br/>Cyclophosphamide--administration & dosage<br/>Diphosphonates--administration & dosage<br/>Enzyme Activation--drug effects<br/>Humans<br/>Imidazoles--administration & dosage<br/>Mice<br/>Mice, Inbred BALB C<br/>Mitogen-Activated Protein Kinase 1--antagonists & inhibitors<br/>Mitogen-Activated Protein Kinase 3--antagonists & inhibitors<br/>Neuroblastoma--drug therapy<br/>Osteoclasts--drug effects<br/>Proto-Oncogene Proteins c-akt--antagonists & inhibitors<br/>Proto-Oncogene Proteins c-bcl-2--antagonists & inhibitors<br/>Topotecan--administration & dosage<br/>Xenograft Model Antitumor Assays<br/>Zoledronic Acid<br/>ras Proteins--metabolism