TY - GEN AU - Chirgwin,John M AU - Guise,Theresa A TI - Skeletal metastases: decreasing tumor burden by targeting the bone microenvironment SN - 0730-2312 PY - 2008///0313 KW - Bone Neoplasms KW - drug therapy KW - Forecasting KW - Humans KW - Models, Biological KW - Neoplasm Metastasis KW - Osteoblasts KW - physiology KW - Osteoclasts KW - Osteolysis KW - genetics KW - Transforming Growth Factor beta KW - Tumor Burden KW - drug effects N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Review UR - https://doi.org/10.1002/jcb.21556 ER -