An analysis of results from 305 compounds tested with the yeast RAD54-GFP genotoxicity assay (GreenScreen GC)-including relative predictivity of regulatory tests and rodent carcinogenesis and performance with autofluorescent and coloured compounds. [electronic resource]
- Mutagenesis Nov 2007
- 409-16 p. digital
Publication Type: Journal Article
0267-8357
10.1093/mutage/gem036 doi
Animals Carcinogens--toxicity Coloring Agents--toxicity Comet Assay DNA Damage DNA Helicases DNA Repair Enzymes Fluorescence Gene Expression Regulation--drug effects Green Fluorescent Proteins--biosynthesis Liver--drug effects Mutagenicity Tests--standards Promoter Regions, Genetic Rats Reproducibility of Results Saccharomyces cerevisiae--drug effects Saccharomyces cerevisiae Proteins--biosynthesis Sensitivity and Specificity