TY - GEN AU - Sheikh,Ahmad Y AU - Chun,Hyung J AU - Glassford,Alexander J AU - Kundu,Ramendera K AU - Kutschka,Ingo AU - Ardigo,Diego AU - Hendry,Stephen L AU - Wagner,Roger A AU - Chen,Mary M AU - Ali,Ziad A AU - Yue,Patrick AU - Huynh,Diem T AU - Connolly,Andrew J AU - Pelletier,Marc P AU - Tsao,Philip S AU - Robbins,Robert C AU - Quertermous,Thomas TI - In vivo genetic profiling and cellular localization of apelin reveals a hypoxia-sensitive, endothelial-centered pathway activated in ischemic heart failure SN - 0363-6135 PY - 2008///0228 KW - Adipokines KW - Animals KW - Apelin KW - Apelin Receptors KW - Basic Helix-Loop-Helix Transcription Factors KW - genetics KW - Carrier Proteins KW - Cell Hypoxia KW - Cells, Cultured KW - Coronary Vessels KW - surgery KW - Disease Models, Animal KW - Endothelial Cells KW - metabolism KW - Female KW - Gene Expression Profiling KW - Genes, Reporter KW - Heart Failure KW - etiology KW - Humans KW - Hypoxia KW - Hypoxia-Inducible Factor 1, alpha Subunit KW - Intercellular Signaling Peptides and Proteins KW - Lac Operon KW - Ligation KW - Lung KW - Mice KW - Mice, Transgenic KW - Myocardial Ischemia KW - complications KW - Myocardium KW - Promoter Regions, Genetic KW - Quadriceps Muscle KW - RNA, Messenger KW - Receptors, G-Protein-Coupled KW - Signal Transduction KW - Time Factors KW - Transfection KW - Up-Regulation N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1152/ajpheart.00935.2007 ER -