TY - GEN AU - Kawasaki,Daisuke AU - Emori,Yutaka AU - Eta,Runa AU - Iino,Yuka AU - Hamano,Hiroki AU - Yoshinaga,Koji AU - Tanaka,Takao AU - Takei,Mineo AU - Watson,Susan A TI - Effect of Z-360, a novel orally active CCK-2/gastrin receptor antagonist on tumor growth in human pancreatic adenocarcinoma cell lines in vivo and mode of action determinations in vitro SN - 0344-5704 PY - 2008///0612 KW - Adenocarcinoma KW - drug therapy KW - Administration, Oral KW - Animals KW - Antineoplastic Agents KW - administration & dosage KW - Antineoplastic Combined Chemotherapy Protocols KW - pharmacology KW - Benzodiazepinones KW - Cell Line, Tumor KW - Cell Proliferation KW - drug effects KW - Deoxycytidine KW - Disease Models, Animal KW - Female KW - Gastrins KW - Humans KW - Mice KW - Mice, Nude KW - Pancreatic Neoplasms KW - Phosphorylation KW - Proto-Oncogene Proteins c-akt KW - Receptor, Cholecystokinin B KW - antagonists & inhibitors KW - Survival Rate KW - Xenograft Model Antitumor Assays KW - Gemcitabine N1 - Publication Type: Journal Article UR - https://doi.org/10.1007/s00280-007-0591-8 ER -