D'Alessandro, Sarah

Differential effects on angiogenesis of two antimalarial compounds, dihydroartemisinin and artemisone: implications for embryotoxicity. [electronic resource] - Toxicology Nov 2007 - 66-74 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0300-483X

10.1016/j.tox.2007.08.084 doi


Adult
Animals
Antimalarials--toxicity
Aorta, Thoracic--drug effects
Artemisinins--toxicity
Capillaries--drug effects
Cell Line
Cell Proliferation--drug effects
Cytokines--biosynthesis
Dose-Response Relationship, Drug
Embryo, Mammalian--pathology
Endothelium, Vascular--drug effects
Enzyme-Linked Immunosorbent Assay
Female
Fibronectins--biosynthesis
Humans
Male
Neovascularization, Physiologic--drug effects
Neural Tube--drug effects
Pregnancy
Rats
Rats, Inbred F344
Sesquiterpenes--toxicity
Teratogens
Tetrazolium Salts
Thiazoles
Vascular Endothelial Growth Factor A--biosynthesis