A variant of mitochondrial protein LOC387715/ARMS2, not HTRA1, is strongly associated with age-related macular degeneration. [electronic resource]
- Proceedings of the National Academy of Sciences of the United States of America Oct 2007
- 16227-32 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
0027-8424
10.1073/pnas.0703933104 doi
Aged Amino Acid Sequence Animals Base Sequence Chromosomes, Human, Pair 10--genetics Conserved Sequence Gene Expression Genetic Predisposition to Disease Genetic Variation Heterozygote High-Temperature Requirement A Serine Peptidase 1 Homozygote Humans Linkage Disequilibrium Macular Degeneration--genetics Mitochondrial Proteins--genetics Molecular Sequence Data Pan troglodytes--genetics Polymorphism, Single Nucleotide Proteins--genetics RNA, Messenger--genetics Retina--metabolism Sequence Homology, Amino Acid Sequence Homology, Nucleic Acid Serine Endopeptidases--genetics