TY  - GEN
AU  - Lyu,Yi Lisa
AU  - Kerrigan,John E
AU  - Lin,Chao-Po
AU  - Azarova,Anna M
AU  - Tsai,Yuan-Chin
AU  - Ban,Yi
AU  - Liu,Leroy F
TI  - Topoisomerase IIbeta mediated DNA double-strand breaks: implications in doxorubicin cardiotoxicity and prevention by dexrazoxane
SN  - 0008-5472
PY  - 2007///1127
KW  - Animals
KW  - Antibiotics, Antineoplastic
KW  - antagonists & inhibitors
KW  - DNA Breaks, Double-Stranded
KW  - DNA Topoisomerases, Type II
KW  - chemistry
KW  - DNA-Binding Proteins
KW  - Doxorubicin
KW  - Drug Interactions
KW  - Heart Diseases
KW  - chemically induced
KW  - Histones
KW  - metabolism
KW  - Humans
KW  - Mice
KW  - Models, Molecular
KW  - Myocytes, Cardiac
KW  - drug effects
KW  - Proteasome Endopeptidase Complex
KW  - Proteasome Inhibitors
KW  - Protein Conformation
KW  - Razoxane
KW  - pharmacology
KW  - Topoisomerase II Inhibitors
N1  - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S
UR  - https://doi.org/10.1158/0008-5472.CAN-07-1649
ER  -