Purification and analysis of proteinase-resistant mutants of recombinant platelet-derived growth factor-BB exhibiting improved biological activity. [electronic resource]
- The Biochemical journal Jan 1992
- 57-65 p. digital
Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
0264-6021
10.1042/bj2810057 doi
3T3 Cells Amino Acid Sequence Animals Base Sequence Blotting, Western Cell Division--drug effects Chromatography, Gel Chromatography, Ion Exchange Cloning, Molecular--methods Electrophoresis, Polyacrylamide Gel Endopeptidases--metabolism Escherichia coli--genetics Genes, Synthetic Humans Inositol Phosphates--metabolism Mice Molecular Sequence Data Molecular Weight Mutagenesis, Site-Directed Plasmids Platelet-Derived Growth Factor--genetics Recombinant Proteins--isolation & purification Restriction Mapping Saccharomyces cerevisiae--genetics Structure-Activity Relationship Transcription, Genetic