TY  - GEN
AU  - Ghosal,Anima
AU  - Ramanathan,Ragu
AU  - Yuan,Yuan
AU  - Hapangama,Neil
AU  - Chowdhury,Swapan K
AU  - Kishnani,Narendra S
AU  - Alton,Kevin B
TI  - Identification of human liver cytochrome P450 enzymes involved in biotransformation of vicriviroc, a CCR5 receptor antagonist
SN  - 0090-9556
PY  - 2008///0103
KW  - Antibodies, Monoclonal
KW  - Aryl Hydrocarbon Hydroxylases
KW  - metabolism
KW  - Biotransformation
KW  - Bridged-Ring Compounds
KW  - pharmacology
KW  - CCR5 Receptor Antagonists
KW  - Carboxylic Acids
KW  - Cytochrome P-450 CYP2C9
KW  - Cytochrome P-450 CYP3A
KW  - Cytochrome P-450 Enzyme Inhibitors
KW  - Cytochrome P-450 Enzyme System
KW  - immunology
KW  - Dealkylation
KW  - Enzyme Inhibitors
KW  - Humans
KW  - Immunologic Factors
KW  - In Vitro Techniques
KW  - Isoenzymes
KW  - Ketoconazole
KW  - Kinetics
KW  - Liver
KW  - drug effects
KW  - Oxidation-Reduction
KW  - Piperazines
KW  - Pyrimidines
KW  - Recombinant Proteins
KW  - Substrate Specificity
KW  - Testosterone
KW  - Triazoles
N1  - Publication Type: Journal Article
UR  - https://doi.org/10.1124/dmd.107.017517
ER  -