Ghosal, Anima <br/><br/>
Identification of human liver cytochrome P450 enzymes involved in biotransformation of vicriviroc, a CCR5 receptor antagonist.  [electronic resource] 

 -  Drug metabolism and disposition: the biological fate of chemicals  Dec 2007 
 - 2186-95 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>0090-9556 
<br/><br/><label>Standard No.: </label>10.1124/dmd.107.017517  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Antibodies, Monoclonal<br/>Aryl Hydrocarbon Hydroxylases--metabolism<br/>Biotransformation<br/>Bridged-Ring Compounds--pharmacology<br/>CCR5 Receptor Antagonists<br/>Carboxylic Acids--metabolism<br/>Cytochrome P-450 CYP2C9<br/>Cytochrome P-450 CYP3A<br/>Cytochrome P-450 Enzyme Inhibitors<br/>Cytochrome P-450 Enzyme System--immunology<br/>Dealkylation<br/>Enzyme Inhibitors--pharmacology<br/>Humans<br/>Immunologic Factors--metabolism<br/>In Vitro Techniques<br/>Isoenzymes--metabolism<br/>Ketoconazole--pharmacology<br/>Kinetics<br/>Liver--drug effects<br/>Oxidation-Reduction<br/>Piperazines--metabolism<br/>Pyrimidines--metabolism<br/>Recombinant Proteins--metabolism<br/>Substrate Specificity<br/>Testosterone--metabolism<br/>Triazoles--pharmacology